Comments on: Average doesn’t tell the whole story http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/ A critical look at nutritional science and anything else that strikes my fancy. Thu, 20 Nov 2008 11:51:55 +0000 http://wordpress.org/?v=2.6.3 By: johnny quick http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-139356 johnny quick Sat, 14 Jun 2008 16:11:36 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-139356 Doctor, this study was not included in Colpo's book. <em>I'm not sure I understand your comment. If you are referring to the study that is the subject of this post, I don't think I ever claimed that it was in his book. Cheers</em> Doctor, this study was not included in Colpo’s book.

I’m not sure I understand your comment. If you are referring to the study that is the subject of this post, I don’t think I ever claimed that it was in his book.

Cheers

]]> By: Cathyvm http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117451 Cathyvm Sat, 29 Mar 2008 23:41:31 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117451 CAC and other calcification is now demonstrated to be connected with calcifying nanoparticles (nanobacteria). They somehow drag hydroxyapatite particles into the cells and form little igloos around themselves making them impervious to some form of modified tetracycline treatment (the only current "treatment"). They appear when the body is stressed in some way. Of course instead of figuring a way to prevent/alleviate the stresses (whether physical, mental or environmental) they have of course patented a new treatment. There is quite a lot of information here: http://www.nanobaclabs.com/content/what-are-cnps.htm <em>Interesting. I'll read it.</em> CAC and other calcification is now demonstrated to be connected with calcifying nanoparticles (nanobacteria). They somehow drag hydroxyapatite particles into the cells and form little igloos around themselves making them impervious to some form of modified tetracycline treatment (the only current “treatment”). They appear when the body is stressed in some way. Of course instead of figuring a way to prevent/alleviate the stresses (whether physical, mental or environmental) they have of course patented a new treatment.
There is quite a lot of information here:
http://www.nanobaclabs.com/content/what-are-cnps.htm

Interesting. I’ll read it.

]]> By: Stuart Buck http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117282 Stuart Buck Fri, 28 Mar 2008 16:02:43 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117282 Never mind, read too quickly, I didn't notice that a couple of the numbers represented positive weight gain. Never mind, read too quickly, I didn’t notice that a couple of the numbers represented positive weight gain.

]]> By: Stuart Buck http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117281 Stuart Buck Fri, 28 Mar 2008 16:00:58 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117281 <i>If you add these numbers up and divide by 10 you find that the average or mean weight loss for the group is 1.6 pounds, which doesn’t seem like a lot.</i> Huh? When I add up the numbers, I get 48. Divided by 10, that's a mean of 4.8 pounds lost. Right? Not 1.6. If you add these numbers up and divide by 10 you find that the average or mean weight loss for the group is 1.6 pounds, which doesn’t seem like a lot.

Huh? When I add up the numbers, I get 48. Divided by 10, that’s a mean of 4.8 pounds lost. Right? Not 1.6.

]]> By: John http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117130 John Fri, 28 Mar 2008 01:12:10 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117130 And the follow-up question everybody probably has: do we have any idea what lifestyle choices affect CAC scores? <em>Well, a couple of major differences between those who had heart attacks and those who didn't were that those who did had significantly higher triglyceride levels and significantly lower HDL-cholesterol levels than those who didn't. We know that restricting carbohydrates markedly reduces triglycerides and increasing fat intake markedly increases HDL-cholesterol. A low-carb diet is a higher-fat diet, so my recommendation is the low-carb diet.</em> And the follow-up question everybody probably has: do we have any idea what lifestyle choices affect CAC scores?

Well, a couple of major differences between those who had heart attacks and those who didn’t were that those who did had significantly higher triglyceride levels and significantly lower HDL-cholesterol levels than those who didn’t. We know that restricting carbohydrates markedly reduces triglycerides and increasing fat intake markedly increases HDL-cholesterol. A low-carb diet is a higher-fat diet, so my recommendation is the low-carb diet.

]]> By: Michael Richards http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117085 Michael Richards Thu, 27 Mar 2008 22:57:00 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117085 Hi again Dr E, Hit Submit too soon. Here is the abstract of the MESA paper: http://content.nejm.org/cgi/content/short/358/13/1336 Michael Richards Hi again Dr E,

Hit Submit too soon. Here is the abstract of the MESA paper:

http://content.nejm.org/cgi/content/short/358/13/1336

Michael Richards

]]> By: Michael Richards http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117084 Michael Richards Thu, 27 Mar 2008 22:52:32 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-117084 Hi Dr E, I've just now come across this post (hat tip: Sandy Szwarc) called The March of the Zealots. It's pretty good. http://www.numberwatch.co.uk/zealots.htm Also, even more off-topic, the Multi-Ethnic Study of Atherosclerosis (MESEA) results are out. http://www.theheart.org/viewArticle.do?primaryKey=849845&nl_id=tho27mar08 (login required) A snip from the article: "The coronary artery calcium (CAC) score is a predictor of coronary heart disease not just in whites but also in blacks, Hispanics, and Chinese, a new analysis of the Multi-Ethnic Study of Atherosclerosis (MESA) study shows. Dr Robert Detrano (University of California, Irvine) and colleagues are the first to examine the relationship between the amount of coronary calcium and the incidence of coronary events in various ethnic groups; they report their findings in the March 27, 2008 issue of the New England Journal of Medicine. "Detrano explained to heartwire that although it is already known that the prevalence and extent of coronary calcification differ substantially among ethnic groups—for example, African Americans are known to have around 40% less calcification than whites—"what we didn't know was whether, when there is calcification, it was as meaningful. We have shown that it is." "His team found that a doubling of calcium scores increased the estimated probability of a major coronary event by around 25% in all the ethnic groups they looked at, over a follow-up period of almost four years—a measure they say adds "incremental" value to the prediction of coronary heart disease over and above standard risk factors. " (Hat tip Dr Davis.) This is really, really strong evidence of the value of Calcium Scores. But will the boffins take notice??? (See above for unfortunate answer) Michael Richards <em>Hey Michael-- I just read this study this morning. If you read all the literature out there you will discover that calcium scores are very predictive of who will have a heart attack and who won't. Those with calcium scores of zero have virtually no chance of having a heart attack (as long as they maintain a zero score) irrespective of what cholesterol levels are. In this very study there was no difference in cholesterol levels between those who developed heart disease and those who didn't. And both groups had total cholesterol levels below 200 mg/dl, which should give the lie to the notion that cholesterol drives heart disease. Interestingly, of the group who developed heart disease, 28.4% were taking statins whereas only 16% of those in the group who didn't develop heart disease were taking statins. Cheers-- MRE </em> Hi Dr E,

I’ve just now come across this post (hat tip: Sandy Szwarc) called The March of the Zealots. It’s pretty good. http://www.numberwatch.co.uk/zealots.htm

Also, even more off-topic, the Multi-Ethnic Study of Atherosclerosis (MESEA) results are out.
http://www.theheart.org/viewArticle.do?primaryKey=849845&nl_id=tho27mar08 (login required)

A snip from the article:
“The coronary artery calcium (CAC) score is a predictor of coronary heart disease not just in whites but also in blacks, Hispanics, and Chinese, a new analysis of the Multi-Ethnic Study of Atherosclerosis (MESA) study shows. Dr Robert Detrano (University of California, Irvine) and colleagues are the first to examine the relationship between the amount of coronary calcium and the incidence of coronary events in various ethnic groups; they report their findings in the March 27, 2008 issue of the New England Journal of Medicine.

“Detrano explained to heartwire that although it is already known that the prevalence and extent of coronary calcification differ substantially among ethnic groups—for example, African Americans are known to have around 40% less calcification than whites—”what we didn’t know was whether, when there is calcification, it was as meaningful. We have shown that it is.”

“His team found that a doubling of calcium scores increased the estimated probability of a major coronary event by around 25% in all the ethnic groups they looked at, over a follow-up period of almost four years—a measure they say adds “incremental” value to the prediction of coronary heart disease over and above standard risk factors. ”
(Hat tip Dr Davis.)

This is really, really strong evidence of the value of Calcium Scores. But will the boffins take notice??? (See above for unfortunate answer)

Michael Richards

Hey Michael–

I just read this study this morning. If you read all the literature out there you will discover that calcium scores are very predictive of who will have a heart attack and who won’t. Those with calcium scores of zero have virtually no chance of having a heart attack (as long as they maintain a zero score) irrespective of what cholesterol levels are. In this very study there was no difference in cholesterol levels between those who developed heart disease and those who didn’t. And both groups had total cholesterol levels below 200 mg/dl, which should give the lie to the notion that cholesterol drives heart disease. Interestingly, of the group who developed heart disease, 28.4% were taking statins whereas only 16% of those in the group who didn’t develop heart disease were taking statins.

Cheers–

MRE

]]> By: simon fellows http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-116679 simon fellows Wed, 26 Mar 2008 23:07:18 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-116679 I know and thats why i sent it. Easily done with cilantro and a bit o salsa. toot n flute sinc. I know and thats why i sent it.
Easily done with cilantro and a bit o salsa.

toot n flute

sinc.

]]> By: Mike G http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-116653 Mike G Wed, 26 Mar 2008 21:21:31 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-116653 Amy, above, is exactly right. The rapidly improving labs and acceptance by the patients certainly validate LC but differentiating metabolic advantage of macronutrients seems like a trivial pursuit. For me, the most remarkable finding was that these diabetic, obese patients quickly found just the right total Kcal without measuring or supervision. Bravo, mother nature and the VLCD Paleolitic diet! Amy, above, is exactly right. The rapidly improving labs and acceptance by the patients certainly validate LC but differentiating metabolic advantage of macronutrients seems like a trivial pursuit. For me, the most remarkable finding was that these diabetic, obese patients quickly found just the right total Kcal without measuring or supervision. Bravo, mother nature and the VLCD Paleolitic diet!

]]> By: simon fellows http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-116646 simon fellows Wed, 26 Mar 2008 20:43:43 +0000 http://www.proteinpower.com/drmike/weight-loss/average-doesn-tell-the-whole-story/#comment-116646 http://www.timesonline.co.uk/tol/life_and_style/food_and_drink/article3559318.ece Have a look at the above for obvious reasons. Saatchi is insanely wealthy...advertising first with his Bro and latterly as a collector of art. But the eggs have it on this one. As bizarre as it sounds i could eat nowt but eggs with a smattering of veggies and speeces. All good things and again the Rad or Fad post on IF was rooty tooty. Rock not Pop, Sister. Sinc. <em>In Protein Power I wrote about a New England Journal of Medicine article describing how an elderly man in a nursing home subsisted entirely on two dozen eggs per day without any ill effects and while keeping all his lipid levels normal. It can be done.</em> http://www.timesonline.co.uk/tol/life_and_style/food_and_drink/article3559318.ece

Have a look at the above for obvious reasons. Saatchi is insanely wealthy…advertising first with his Bro and latterly as a collector of art.
But the eggs have it on this one.

As bizarre as it sounds i could eat nowt but eggs with a smattering of veggies and speeces.

All good things and again the Rad or Fad post on IF was rooty tooty.

Rock not Pop, Sister.

Sinc.

In Protein Power I wrote about a New England Journal of Medicine article describing how an elderly man in a nursing home subsisted entirely on two dozen eggs per day without any ill effects and while keeping all his lipid levels normal. It can be done.

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