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	<title>Comments on: Protein sparing effect</title>
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	<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/</link>
	<description>A critical look at nutritional science and anything else that strikes my fancy.</description>
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		<title>By: Manaloa</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-90985</link>
		<dc:creator>Manaloa</dc:creator>
		<pubDate>Fri, 18 Jan 2008 00:06:34 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-90985</guid>
		<description>&quot;We get some sugar from the breakdown of fat, but not much. Triglycerides, i.e., stored fat, are made of three fatty acids attached to a glycerol backbone. When the fatty acids that we are burning for energy are stripped away from the glycerol, the liver converts these left-over glycerol molecules into glucose. Most of our sugar, however, comes from the breakdown of muscle tissue. The liver converts certain amino acids that make up muscle into sugar in a process called gluconeogenesis.&quot; [Quote]

So what is the amount of fat broken down for sugar dependent on? Assuming vlc/no carb &amp; high fat intake?

&lt;em&gt;The amount of sugar that comes from the breakdown of fat is fairly small, maybe 10 percent of the total.  But it&#039;s dependent on only the breakdown of fat.  If fat breaks down, the fatty acids are stripped from the glycerol backbone.  This glycerol is then freed up to be used for conversion to glucose.  It doesn&#039;t matter whether th fat breakdown happens during low-carb dieting or low-fat dieting, the glycerol is released just the same.  But more fat will be broken down during a low-carb diet, meaning that more glycerol will be released.

Cheers--

MRE&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>&#8220;We get some sugar from the breakdown of fat, but not much. Triglycerides, i.e., stored fat, are made of three fatty acids attached to a glycerol backbone. When the fatty acids that we are burning for energy are stripped away from the glycerol, the liver converts these left-over glycerol molecules into glucose. Most of our sugar, however, comes from the breakdown of muscle tissue. The liver converts certain amino acids that make up muscle into sugar in a process called gluconeogenesis.&#8221; [Quote]</p>
<p>So what is the amount of fat broken down for sugar dependent on? Assuming vlc/no carb &amp; high fat intake?</p>
<p><em>The amount of sugar that comes from the breakdown of fat is fairly small, maybe 10 percent of the total.  But it&#8217;s dependent on only the breakdown of fat.  If fat breaks down, the fatty acids are stripped from the glycerol backbone.  This glycerol is then freed up to be used for conversion to glucose.  It doesn&#8217;t matter whether th fat breakdown happens during low-carb dieting or low-fat dieting, the glycerol is released just the same.  But more fat will be broken down during a low-carb diet, meaning that more glycerol will be released.</p>
<p>Cheers&#8211;</p>
<p>MRE</em></p>
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		<title>By: Gil</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-53688</link>
		<dc:creator>Gil</dc:creator>
		<pubDate>Fri, 28 Sep 2007 18:16:43 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-53688</guid>
		<description>one more thing: 
Want to make it clear that I have never taken anything
even remotely resembling &quot;hormones or their precursors&quot;.
Though I have an innate ability (probably low myostatin)
to build muscle it is besides the point that I feel better,
have more muscle and much, much better energy etc...
Gil

Thanks for the addendum.</description>
		<content:encoded><![CDATA[<p>one more thing:<br />
Want to make it clear that I have never taken anything<br />
even remotely resembling &#8220;hormones or their precursors&#8221;.<br />
Though I have an innate ability (probably low myostatin)<br />
to build muscle it is besides the point that I feel better,<br />
have more muscle and much, much better energy etc&#8230;<br />
Gil</p>
<p>Thanks for the addendum.</p>
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		<title>By: Gil</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-53685</link>
		<dc:creator>Gil</dc:creator>
		<pubDate>Fri, 28 Sep 2007 18:05:03 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-53685</guid>
		<description>the testosterone &quot;thing&quot; has been a BIG deal with nay-sayers of low-carbing. 
I AM the best of examples. I feel stronger afer a long, hard bike ride than before. My sex-drive is pronouncely better. 

For those of you out there with Bodybuilding concerns, I want to tell you this.
I was always able to build muscle through workouts my whole life. 
A few years ago, I was diagnosed with type II and hypothyroid. 
After reading Protein Power, I went full-bore with high protein/fats and low-to-zero carbs.

EVERYTHING changed for the better. My muscle tone is awesome: arms - 20.5&quot;, chest 51&quot;, wear 36-38 pants (depending on leg cut). Strength is BEST with strictest carb-intake.
Every once in a while, I eat some carbs because I want to. Always feel worse for it.

I can ride a bike for many, many miles WITHOUT EATING a thing and ingest only water and feel great. In fact, soon as I eat something, strength/energy level goes DOWN immediately after.

I cannot believe that I am unique or some sort of aberation. 
One advice: IF you eat lots of carbs one day, do the following: 
1- WORKOUT  the next morning on empty stomach - after sluggish start, you will feel great.
2- Eat later in day: PROTEIN/FATS only.

From the Lab that is my body,
Gil

&lt;em&gt;Hi Gil--

Thanks for the dietary and workout history.  I&#039;m glad you&#039;ve found what works best for you.  Keep after it.

Cheers--

MRE&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>the testosterone &#8220;thing&#8221; has been a BIG deal with nay-sayers of low-carbing.<br />
I AM the best of examples. I feel stronger afer a long, hard bike ride than before. My sex-drive is pronouncely better. </p>
<p>For those of you out there with Bodybuilding concerns, I want to tell you this.<br />
I was always able to build muscle through workouts my whole life.<br />
A few years ago, I was diagnosed with type II and hypothyroid.<br />
After reading Protein Power, I went full-bore with high protein/fats and low-to-zero carbs.</p>
<p>EVERYTHING changed for the better. My muscle tone is awesome: arms &#8211; 20.5&#8243;, chest 51&#8243;, wear 36-38 pants (depending on leg cut). Strength is BEST with strictest carb-intake.<br />
Every once in a while, I eat some carbs because I want to. Always feel worse for it.</p>
<p>I can ride a bike for many, many miles WITHOUT EATING a thing and ingest only water and feel great. In fact, soon as I eat something, strength/energy level goes DOWN immediately after.</p>
<p>I cannot believe that I am unique or some sort of aberation.<br />
One advice: IF you eat lots of carbs one day, do the following:<br />
1- WORKOUT  the next morning on empty stomach &#8211; after sluggish start, you will feel great.<br />
2- Eat later in day: PROTEIN/FATS only.</p>
<p>From the Lab that is my body,<br />
Gil</p>
<p><em>Hi Gil&#8211;</p>
<p>Thanks for the dietary and workout history.  I&#8217;m glad you&#8217;ve found what works best for you.  Keep after it.</p>
<p>Cheers&#8211;</p>
<p>MRE</em></p>
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		<title>By: Michael Donofrio</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-493</link>
		<dc:creator>Michael Donofrio</dc:creator>
		<pubDate>Sat, 15 Jul 2006 11:01:10 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-493</guid>
		<description>Hello, I have a question that is a follow-up to one of your responses posted on 6/21/06 above:  You stated that, &quot;One of the problems with insulin resistance is that elevated levels of insulin convert estrogen into testosterone in women. Were they to lower their insulin levels, which is easily done with a low-carb diet, they wouldn&#039;t have nearly as much free testosterone to worry about.&quot;  This statement contradicts my understanding that low carb dieting helps to keep testosterone levels higher, and that extreme low fat diets tend to cause T levels to plummet.  Are you applying this statement to women only?  As a male who is starting his middle age years,  I am trying to keep my T levels as high as possible naturally, and I have read that low carb is one of the best ways to do so.  Your thoughts are appreciated.

Hi Michael--

Thanks for the question--I should have been a little clearer.  As far as sex hormones are concerned, elevated insulin levels cause different in men than is women.  In women, as I mentioned, hyperinsulinemia tends to convert estrogen to testosterone, which is why many obese women, especially obese women with PCS, are often masculinized.  They sometimes develop facial hair and male pattern baldness.  In men hyperinsulinemia causes the testosterone to convert to estrogen, which is why many obese men develop breasts, decreased facial hair, and other feminine characteristics.  Body builders have a problem with this because they often want elevated insulin levels to pack on the muscle and end up with breasts.  You are on the right track with a low-carb diet; it will ensure that you will get maximum benefit from all your own testosterone.

Hope this answers your question.

MRE 
</description>
		<content:encoded><![CDATA[<p>Hello, I have a question that is a follow-up to one of your responses posted on 6/21/06 above:  You stated that, &#8220;One of the problems with insulin resistance is that elevated levels of insulin convert estrogen into testosterone in women. Were they to lower their insulin levels, which is easily done with a low-carb diet, they wouldn&#8217;t have nearly as much free testosterone to worry about.&#8221;  This statement contradicts my understanding that low carb dieting helps to keep testosterone levels higher, and that extreme low fat diets tend to cause T levels to plummet.  Are you applying this statement to women only?  As a male who is starting his middle age years,  I am trying to keep my T levels as high as possible naturally, and I have read that low carb is one of the best ways to do so.  Your thoughts are appreciated.</p>
<p>Hi Michael&#8211;</p>
<p>Thanks for the question&#8211;I should have been a little clearer.  As far as sex hormones are concerned, elevated insulin levels cause different in men than is women.  In women, as I mentioned, hyperinsulinemia tends to convert estrogen to testosterone, which is why many obese women, especially obese women with PCS, are often masculinized.  They sometimes develop facial hair and male pattern baldness.  In men hyperinsulinemia causes the testosterone to convert to estrogen, which is why many obese men develop breasts, decreased facial hair, and other feminine characteristics.  Body builders have a problem with this because they often want elevated insulin levels to pack on the muscle and end up with breasts.  You are on the right track with a low-carb diet; it will ensure that you will get maximum benefit from all your own testosterone.</p>
<p>Hope this answers your question.</p>
<p>MRE </p>
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		<title>By: imsovain</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-492</link>
		<dc:creator>imsovain</dc:creator>
		<pubDate>Fri, 14 Jul 2006 18:22:34 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-492</guid>
		<description>By the way, what&#039;s up with Dr. Rosedale&#039;s lack of a web presence?  I ask because you mention him in PPLP.   He has a website, but it only seems accessible by password.  Is he too busy with real patients?  Was he besieged by annoying questions by random people on the Internet like me?  Did he not get enough business from his website to justify his time?  Nosy people want to know!

I haven&#039;t spoken with Dr. Rosedale for about a year and a half.  I don&#039;t have a clue as to what&#039;s happening with his website, or to him, for that matter.  He and I are going to debate optimal protein intake at a medical meeting in San Diego in October.  I&#039;m sure we&#039;ll get together for dinner or something while we&#039;re there and catch up.  I&#039;ll keep you posted.

MRE</description>
		<content:encoded><![CDATA[<p>By the way, what&#8217;s up with Dr. Rosedale&#8217;s lack of a web presence?  I ask because you mention him in PPLP.   He has a website, but it only seems accessible by password.  Is he too busy with real patients?  Was he besieged by annoying questions by random people on the Internet like me?  Did he not get enough business from his website to justify his time?  Nosy people want to know!</p>
<p>I haven&#8217;t spoken with Dr. Rosedale for about a year and a half.  I don&#8217;t have a clue as to what&#8217;s happening with his website, or to him, for that matter.  He and I are going to debate optimal protein intake at a medical meeting in San Diego in October.  I&#8217;m sure we&#8217;ll get together for dinner or something while we&#8217;re there and catch up.  I&#8217;ll keep you posted.</p>
<p>MRE</p>
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		<title>By: imsovain</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-491</link>
		<dc:creator>imsovain</dc:creator>
		<pubDate>Wed, 05 Jul 2006 19:28:21 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-491</guid>
		<description>I recently read &quot;The Rosedale Diet&quot; and Rosedale recommends less protein than you do (.5 g protein/ lb lean body mass, add 10 g protein &quot;if you are a heavy exerciser&quot;).  He also seems to believe that excess consumed protein will be turned into sugar, which in turn is converted to excess fat.  On the other hand, you state that &quot;dietary protein turning to fat is not something we really need to worry about&quot;.

Is this a point on which reasonable people can disagree or do you think Rosedale is pretty much wrong?

Hi Imsovain--

Rosedale and I have a difference of opinion on the issue I suppose.  In fact he and I are going to debate the how-much-protein-is-enough issue in a public forum at the American Society of Bariatric Physicians national meeting this October in San Diego.  I&#039;ll keep you posted as I put together my material because the issue isn&#039;t a simple one that can be explained in a sentence or two.  And there is a big difference in how much protein is required on a low-carb diet verses a high-carb diet.

Best--

MRE</description>
		<content:encoded><![CDATA[<p>I recently read &#8220;The Rosedale Diet&#8221; and Rosedale recommends less protein than you do (.5 g protein/ lb lean body mass, add 10 g protein &#8220;if you are a heavy exerciser&#8221;).  He also seems to believe that excess consumed protein will be turned into sugar, which in turn is converted to excess fat.  On the other hand, you state that &#8220;dietary protein turning to fat is not something we really need to worry about&#8221;.</p>
<p>Is this a point on which reasonable people can disagree or do you think Rosedale is pretty much wrong?</p>
<p>Hi Imsovain&#8211;</p>
<p>Rosedale and I have a difference of opinion on the issue I suppose.  In fact he and I are going to debate the how-much-protein-is-enough issue in a public forum at the American Society of Bariatric Physicians national meeting this October in San Diego.  I&#8217;ll keep you posted as I put together my material because the issue isn&#8217;t a simple one that can be explained in a sentence or two.  And there is a big difference in how much protein is required on a low-carb diet verses a high-carb diet.</p>
<p>Best&#8211;</p>
<p>MRE</p>
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		<title>By: simon Fellows</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-490</link>
		<dc:creator>simon Fellows</dc:creator>
		<pubDate>Thu, 29 Jun 2006 12:12:04 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-490</guid>
		<description>Victoria Hi....have you tried doing rampantly less weights ? I know it sounds counter-intuitive (read Myers wonderful book Intuition its powers and perils) but i would think you&#039;d be suprised.
Our genome isn&#039;t adpated to rote repeticious steady state activities.
&#039;Ope of use</description>
		<content:encoded><![CDATA[<p>Victoria Hi&#8230;.have you tried doing rampantly less weights ? I know it sounds counter-intuitive (read Myers wonderful book Intuition its powers and perils) but i would think you&#8217;d be suprised.<br />
Our genome isn&#8217;t adpated to rote repeticious steady state activities.<br />
&#8216;Ope of use</p>
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		<title>By: Victoria</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-489</link>
		<dc:creator>Victoria</dc:creator>
		<pubDate>Mon, 26 Jun 2006 22:32:12 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-489</guid>
		<description>&gt;The recomposition issue is an important one that many people lose sight of in their focus on weight loss. No one sees weight; everyone sees size. It makes much more since to work on reducing size, but it seems that everyone monitors themselves on the scale.&lt;

I&#039;ve never been able to gain muscle, no matter how hard I hit the weights or how much protein I eat before and after my workout.  So my weight stays the same, and my dress size stays the same.  :(  I do 30 minutes of weight training and other muscle exercises 2-4 times a week depending on my schedule.</description>
		<content:encoded><![CDATA[<p>&gt;The recomposition issue is an important one that many people lose sight of in their focus on weight loss. No one sees weight; everyone sees size. It makes much more since to work on reducing size, but it seems that everyone monitors themselves on the scale.&lt;</p>
<p>I&#8217;ve never been able to gain muscle, no matter how hard I hit the weights or how much protein I eat before and after my workout.  So my weight stays the same, and my dress size stays the same.  <img src='http://www.proteinpower.com/drmike/wp-includes/images/smilies/icon_sad.gif' alt=':(' class='wp-smiley' />   I do 30 minutes of weight training and other muscle exercises 2-4 times a week depending on my schedule.</p>
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		<title>By: simon Fellows</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-488</link>
		<dc:creator>simon Fellows</dc:creator>
		<pubDate>Sun, 25 Jun 2006 17:18:16 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-488</guid>
		<description>Sir Hola..given that your work has a paleothrust/bent in premise would you be prepared to comment on fasting and its uses to the &#039;uman system, pleasum, given that we of course evolved to have periodic fasting given the erraticism of the enviornment in which we lived within.

Hunger was of course the natural state of man til uber recently and though most all the worlds religions use fasting as a way of clearing consciousness/shifting biopsych blockages its seems its seldom ever mentioned unless by people who are  wearing purple or dancing around with stalactite swinging from  their swedes(heads) i.e  people who don&#039;t come off as being partic.  well informed i.e in this case YEE !
Would you or your MRS  be prepared to open up about fasting and its problems and efficacy&#039;s ?

Thanks muchly.

Sinc.

Simon (Fellows)

Hi Simon.

Good to hear from you; you&#039;ve been lying low lately.

I&#039;ve given a lot of thought to the fasting issue.  I try to look at everything through the lens of our Paleolithic background, and  based on that I can only conclude that fasting--at least in the short term--had to have been a common occurrence for our early ancestors.  The medical literature is rife with papers showing multiple health improvements with short term (i.e., a day or so) fasting.  One of the more recent papers demonstrated the same thing that Zammet found 15 years ago, namely that pulsatile insulin secretion (that found when episodes of eating are separated in time, i.e., no constant snacking) increases insulin sensitivity in the liver whereas constant insulin stimulation (like that found in people who are always on the eat) promotes liver insulin resistance.

On the whole the data seems to show that going a day or so at a time every now without food is a pretty good thing.  Even limiting food intake to a couple of times a day without between meal snacking seems to be a good thing.  I don&#039;t know where this nimrod advocating the latest eat-every-three-hour diet got his data; it sure wasn&#039;t from the medical literature.  I guess if you tell people what they want to hear...

Thanks for writing.

MRE</description>
		<content:encoded><![CDATA[<p>Sir Hola..given that your work has a paleothrust/bent in premise would you be prepared to comment on fasting and its uses to the &#8216;uman system, pleasum, given that we of course evolved to have periodic fasting given the erraticism of the enviornment in which we lived within.</p>
<p>Hunger was of course the natural state of man til uber recently and though most all the worlds religions use fasting as a way of clearing consciousness/shifting biopsych blockages its seems its seldom ever mentioned unless by people who are  wearing purple or dancing around with stalactite swinging from  their swedes(heads) i.e  people who don&#8217;t come off as being partic.  well informed i.e in this case YEE !<br />
Would you or your MRS  be prepared to open up about fasting and its problems and efficacy&#8217;s ?</p>
<p>Thanks muchly.</p>
<p>Sinc.</p>
<p>Simon (Fellows)</p>
<p>Hi Simon.</p>
<p>Good to hear from you; you&#8217;ve been lying low lately.</p>
<p>I&#8217;ve given a lot of thought to the fasting issue.  I try to look at everything through the lens of our Paleolithic background, and  based on that I can only conclude that fasting&#8211;at least in the short term&#8211;had to have been a common occurrence for our early ancestors.  The medical literature is rife with papers showing multiple health improvements with short term (i.e., a day or so) fasting.  One of the more recent papers demonstrated the same thing that Zammet found 15 years ago, namely that pulsatile insulin secretion (that found when episodes of eating are separated in time, i.e., no constant snacking) increases insulin sensitivity in the liver whereas constant insulin stimulation (like that found in people who are always on the eat) promotes liver insulin resistance.</p>
<p>On the whole the data seems to show that going a day or so at a time every now without food is a pretty good thing.  Even limiting food intake to a couple of times a day without between meal snacking seems to be a good thing.  I don&#8217;t know where this nimrod advocating the latest eat-every-three-hour diet got his data; it sure wasn&#8217;t from the medical literature.  I guess if you tell people what they want to hear&#8230;</p>
<p>Thanks for writing.</p>
<p>MRE</p>
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		<title>By: Gabriel E. Guzman, Ph.D.</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/protein-sparing-effect/comment-page-1/#comment-487</link>
		<dc:creator>Gabriel E. Guzman, Ph.D.</dc:creator>
		<pubDate>Sun, 25 Jun 2006 11:15:11 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=259#comment-487</guid>
		<description>I think that what bodybuilder sites tend to ignore or dismiss is that insulin is not the only anabolic hormone involved in muscle mass development.  I think they forget or don&#039;t know that it is in fact Insulin-like growth factor-1 (IGF-1) that has a more prolonged effect in muscle protein synthesis.  Even more important is the fact that in order for IGF-1 to be released, there needs to be a little bit of growth hormone release as well to trigger the release of IGF-1, which can act during the next 20+ hours after a very intense workout such as that of a bodybuilder.  Loads of sugar, however, are one of the best ways of missing the growth hormone boat as its release is hampered.  You also wrote about that in your books.

I&#039;ve had similar questions in the past regarding the amount of protein we eat on Protein Power and the &#039;risks&#039; of uncontrolled production of sugar through gluconeogenesis.  What seems to be missed by some popular naysayers is that just because there is a certain amount of protein coming in the diet, that doesn&#039;t mean that glucose is going to be made immediately without any hormonal regulation.  Uncontrolled diabetics may be a special case because there may be overproduction of glucose, precisely because they&#039;re unresponsive to insulin so gluconeogenesis can&#039;t be shut down efficiently.

As a side note, when I was reading comments about stalling while eating more protein, something that has also been discussed in the past on the Protein Power discussion board, is that since protein also helps keeping lean body mass from vanishing, weight loss tracked via the scale starts to lose its meaning.  Body recomposition (i.e. change in clothes sizes and/or body fat percentage measurements) instead of &#039;total&#039; body weight, on the other hand, is a better way of tracking any changes.  This is even more pronounced when people incorporate regular resistance exercise along with Protein Power.

The argument all the time is that is all we say seems to be true, then why is it that bodybuilders aren&#039;t obese? The question would be relevant if we didn&#039;t consider that bodybuilders are in one end of a spectrum of exercise... Even their diets are tailored to their &#039;specific&#039; requirements.  The problem seems to be that some people like to apply the principles of the bodybuilder&#039;s diet to non-bodybuilders or even &#039;sedentary&#039;.  It is no wonder what would happen to a bodybuilder who keeps eating the same way without exercising any more... where would all those carbs go? Exactly where you think they do.

Hi Gabe--

I think you&#039;re right on the mark.  It is the IGF-1 that&#039;s important, which does require a little spurt of growth hormone.  The growth hormone can be completely blocked by dietary carb immediately after the workout, even if consumed in only tiny amounts.

The recomposition issue is an important one that many people lose sight of in their focus on weight loss.  No one sees weight; everyone sees size.  It makes much more since to work on reducing size, but it seems that everyone monitors themselves on the scale.

Thanks for writing.

MRE</description>
		<content:encoded><![CDATA[<p>I think that what bodybuilder sites tend to ignore or dismiss is that insulin is not the only anabolic hormone involved in muscle mass development.  I think they forget or don&#8217;t know that it is in fact Insulin-like growth factor-1 (IGF-1) that has a more prolonged effect in muscle protein synthesis.  Even more important is the fact that in order for IGF-1 to be released, there needs to be a little bit of growth hormone release as well to trigger the release of IGF-1, which can act during the next 20+ hours after a very intense workout such as that of a bodybuilder.  Loads of sugar, however, are one of the best ways of missing the growth hormone boat as its release is hampered.  You also wrote about that in your books.</p>
<p>I&#8217;ve had similar questions in the past regarding the amount of protein we eat on Protein Power and the &#8216;risks&#8217; of uncontrolled production of sugar through gluconeogenesis.  What seems to be missed by some popular naysayers is that just because there is a certain amount of protein coming in the diet, that doesn&#8217;t mean that glucose is going to be made immediately without any hormonal regulation.  Uncontrolled diabetics may be a special case because there may be overproduction of glucose, precisely because they&#8217;re unresponsive to insulin so gluconeogenesis can&#8217;t be shut down efficiently.</p>
<p>As a side note, when I was reading comments about stalling while eating more protein, something that has also been discussed in the past on the Protein Power discussion board, is that since protein also helps keeping lean body mass from vanishing, weight loss tracked via the scale starts to lose its meaning.  Body recomposition (i.e. change in clothes sizes and/or body fat percentage measurements) instead of &#8216;total&#8217; body weight, on the other hand, is a better way of tracking any changes.  This is even more pronounced when people incorporate regular resistance exercise along with Protein Power.</p>
<p>The argument all the time is that is all we say seems to be true, then why is it that bodybuilders aren&#8217;t obese? The question would be relevant if we didn&#8217;t consider that bodybuilders are in one end of a spectrum of exercise&#8230; Even their diets are tailored to their &#8216;specific&#8217; requirements.  The problem seems to be that some people like to apply the principles of the bodybuilder&#8217;s diet to non-bodybuilders or even &#8216;sedentary&#8217;.  It is no wonder what would happen to a bodybuilder who keeps eating the same way without exercising any more&#8230; where would all those carbs go? Exactly where you think they do.</p>
<p>Hi Gabe&#8211;</p>
<p>I think you&#8217;re right on the mark.  It is the IGF-1 that&#8217;s important, which does require a little spurt of growth hormone.  The growth hormone can be completely blocked by dietary carb immediately after the workout, even if consumed in only tiny amounts.</p>
<p>The recomposition issue is an important one that many people lose sight of in their focus on weight loss.  No one sees weight; everyone sees size.  It makes much more since to work on reducing size, but it seems that everyone monitors themselves on the scale.</p>
<p>Thanks for writing.</p>
<p>MRE</p>
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