<?xml version="1.0" encoding="ISO-8859-1"?><rss version="2.0"
	xmlns:content="http://purl.org/rss/1.0/modules/content/"
	xmlns:dc="http://purl.org/dc/elements/1.1/"
	xmlns:atom="http://www.w3.org/2005/Atom"
	xmlns:sy="http://purl.org/rss/1.0/modules/syndication/"
		>
<channel>
	<title>Comments on: Another one bites the dust</title>
	<atom:link href="http://www.proteinpower.com/drmike/uncategorized/another-one-bites-the-dust/feed/" rel="self" type="application/rss+xml" />
	<link>http://www.proteinpower.com/drmike/uncategorized/another-one-bites-the-dust/</link>
	<description>A critical look at nutritional science and anything else that strikes my fancy.</description>
	<lastBuildDate>Thu, 09 Feb 2012 14:38:34 +0000</lastBuildDate>
	<sy:updatePeriod>hourly</sy:updatePeriod>
	<sy:updateFrequency>1</sy:updateFrequency>
	<generator>http://wordpress.org/?v=3.3.1</generator>
<xhtml:meta xmlns:xhtml="http://www.w3.org/1999/xhtml" name="robots" content="noindex" />
	<item>
		<title>By: Alcinda Moore</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/another-one-bites-the-dust/#comment-236</link>
		<dc:creator>Alcinda Moore</dc:creator>
		<pubDate>Sat, 25 Feb 2006 01:52:25 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=220#comment-236</guid>
		<description>Severe salt restriction has been something I&#039;ve been fighting for years!!!! I can&#039;t tell you how many people I know that treat salt as if it&#039;s poison....and they try to get as low an intake as possible. Pointing out the dangers of low serum sodium seems to fall on deaf ears. I&#039;ve even heard people say they&#039;ve been told they have low serum sodium by their docs, but still refuse to increase their intake! 

I fear though, that this report, like the ones on low fat, will be disputed as being flawed and the medical community will continue to tell people to avoid salt at all costs! 

Alcinda
</description>
		<content:encoded><![CDATA[<p>Severe salt restriction has been something I&#8217;ve been fighting for years!!!! I can&#8217;t tell you how many people I know that treat salt as if it&#8217;s poison&#8230;.and they try to get as low an intake as possible. Pointing out the dangers of low serum sodium seems to fall on deaf ears. I&#8217;ve even heard people say they&#8217;ve been told they have low serum sodium by their docs, but still refuse to increase their intake! </p>
<p>I fear though, that this report, like the ones on low fat, will be disputed as being flawed and the medical community will continue to tell people to avoid salt at all costs! </p>
<p>Alcinda</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Michael R. Eades, MD</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/another-one-bites-the-dust/#comment-235</link>
		<dc:creator>Michael R. Eades, MD</dc:creator>
		<pubDate>Fri, 24 Feb 2006 14:09:25 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=220#comment-235</guid>
		<description>You are absolutely correct.  I&#039;m glad I&#039;ve got a real statistician looking over my shoulder.</description>
		<content:encoded><![CDATA[<p>You are absolutely correct.  I&#8217;m glad I&#8217;ve got a real statistician looking over my shoulder.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Mark Levin</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/another-one-bites-the-dust/#comment-234</link>
		<dc:creator>Mark Levin</dc:creator>
		<pubDate>Fri, 24 Feb 2006 12:12:20 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=220#comment-234</guid>
		<description>Those not found to be deceased were assumed alive at that date.

	This strikes me as a statistical fudge to increase the significance of the results. The best way to deal with people lost to follow-up is to drop them from all statistical calculations and therefore results. 
	The next best, in my opinion, is to assume that they had a similar mortality rate to the population with follow-up. It is unreasonable to assume that everybody lost to follow-up at that point is still alive. Approximately 19% (1343 out of 7154) of the rest of this sample were deceased at the time of the analysis.
	 This would seem to create a negative bias (i.e. that the study is understating the significance of the data)  to the results because it is clear that there would have been deaths in this subgroup. If (admittedly a very big if) they were similar to the larger group, it would strengthen the association between lower salt intake and total mortality and possibly the other mortalities. In my quick glance at the paper, it is unclear how many were lost to follow-up. 
	However or possibly in addition to the negative bias,  it also needs to be taken into consideration that counting the missing data points as having determinate outcomes (i.e. they are alive) unfairly strengthens the statistical power of the results, creating a positive bias to the results,(i.e.  the study is overstating the significance of the data).
	Thanks in advance for allowing me the space to use this blog to express my viewpoint or  to stimulate my thought processes if you donâ€™t choose to publish it.</description>
		<content:encoded><![CDATA[<p>Those not found to be deceased were assumed alive at that date.</p>
<p>	This strikes me as a statistical fudge to increase the significance of the results. The best way to deal with people lost to follow-up is to drop them from all statistical calculations and therefore results.<br />
	The next best, in my opinion, is to assume that they had a similar mortality rate to the population with follow-up. It is unreasonable to assume that everybody lost to follow-up at that point is still alive. Approximately 19% (1343 out of 7154) of the rest of this sample were deceased at the time of the analysis.<br />
	 This would seem to create a negative bias (i.e. that the study is understating the significance of the data)  to the results because it is clear that there would have been deaths in this subgroup. If (admittedly a very big if) they were similar to the larger group, it would strengthen the association between lower salt intake and total mortality and possibly the other mortalities. In my quick glance at the paper, it is unclear how many were lost to follow-up.<br />
	However or possibly in addition to the negative bias,  it also needs to be taken into consideration that counting the missing data points as having determinate outcomes (i.e. they are alive) unfairly strengthens the statistical power of the results, creating a positive bias to the results,(i.e.  the study is overstating the significance of the data).<br />
	Thanks in advance for allowing me the space to use this blog to express my viewpoint or  to stimulate my thought processes if you donâ€™t choose to publish it.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Jack</title>
		<link>http://www.proteinpower.com/drmike/uncategorized/another-one-bites-the-dust/#comment-233</link>
		<dc:creator>Jack</dc:creator>
		<pubDate>Fri, 24 Feb 2006 00:36:20 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike_blog/?p=220#comment-233</guid>
		<description>Excellent article/analysis Dr.Eades.  
   (and thanks for the math lesson!)</description>
		<content:encoded><![CDATA[<p>Excellent article/analysis Dr.Eades.<br />
   (and thanks for the math lesson!)</p>
]]></content:encoded>
	</item>
</channel>
</rss>

