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	<title>Comments on: Thiamin and diabetic nephropathy</title>
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	<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/</link>
	<description>A critical look at nutritional science and anything else that strikes my fancy.</description>
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		<title>By: dianne gariepy</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-243710</link>
		<dc:creator>dianne gariepy</dc:creator>
		<pubDate>Fri, 19 Mar 2010 17:37:35 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-243710</guid>
		<description>well here it is almost a year later.  Here is what I found out in regards to B1.  I used to think that I was walking on marbles from the neraphaty thing (Don&#039;t have a clue on the spelling. ).  So up until feb of this year I was taking one or two B1 vits a day.  Got pretty use to having no foot pain or weird feeling s in my legs or feet.  Then I stopped.  The pains came back tenfold.

So B1 works very well.</description>
		<content:encoded><![CDATA[<p>well here it is almost a year later.  Here is what I found out in regards to B1.  I used to think that I was walking on marbles from the neraphaty thing (Don&#8217;t have a clue on the spelling. ).  So up until feb of this year I was taking one or two B1 vits a day.  Got pretty use to having no foot pain or weird feeling s in my legs or feet.  Then I stopped.  The pains came back tenfold.</p>
<p>So B1 works very well.</p>
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		<title>By: Charles Savoie</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-243408</link>
		<dc:creator>Charles Savoie</dc:creator>
		<pubDate>Wed, 10 Mar 2010 07:32:56 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-243408</guid>
		<description>In free access Archives of site referenced I detail my personal experience using naturally occurring citric acid to reverse calcification of the arteries.  It also occurred to me that the same modality is of renal benefit as a person could have kidney stones without realizing it, and the citric acid would have the same curative, restorative effect of dissolving them, holding them in solution, and passing them as liquid waste.  &quot;Living To Enjoy My Silver.&quot;  Tonight I ordered 720 Benfotiamine capsules of 250mg potency and may take with bioperine.  And it&#039;s back to one corny dog meal per week with lots of mustard so I can realize benefits of isothiocyanates.  Next, TA-65, deer antler polypeptides, carnosine and colostrum.</description>
		<content:encoded><![CDATA[<p>In free access Archives of site referenced I detail my personal experience using naturally occurring citric acid to reverse calcification of the arteries.  It also occurred to me that the same modality is of renal benefit as a person could have kidney stones without realizing it, and the citric acid would have the same curative, restorative effect of dissolving them, holding them in solution, and passing them as liquid waste.  &#8220;Living To Enjoy My Silver.&#8221;  Tonight I ordered 720 Benfotiamine capsules of 250mg potency and may take with bioperine.  And it&#8217;s back to one corny dog meal per week with lots of mustard so I can realize benefits of isothiocyanates.  Next, TA-65, deer antler polypeptides, carnosine and colostrum.</p>
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		<title>By: Laura (Paleo Huntress)</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-213411</link>
		<dc:creator>Laura (Paleo Huntress)</dc:creator>
		<pubDate>Mon, 04 May 2009 01:37:23 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-213411</guid>
		<description>Shoot!  I clicked the next page button and didn&#039;t realize I&#039;d moved to another article. My comment was meant for the villagers vs hunters article.  My bad!  

Paleo Huntress</description>
		<content:encoded><![CDATA[<p>Shoot!  I clicked the next page button and didn&#8217;t realize I&#8217;d moved to another article. My comment was meant for the villagers vs hunters article.  My bad!  </p>
<p>Paleo Huntress</p>
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		<title>By: Laura (Paleo Huntress)</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-213409</link>
		<dc:creator>Laura (Paleo Huntress)</dc:creator>
		<pubDate>Mon, 04 May 2009 01:27:52 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-213409</guid>
		<description>Dr. Eades,

I maintain a paleo-health community online (but do NOT subscribe to the low-fat PC&#039;d book version of the diet) and regularly share entries from this blog with its members- THIS one was especially significant to us. One of the arguments I get quite a bit from newbies is about all of the &quot;protein&quot; in legumes, and whole grains, blah blah. I don&#039;t eat a raw diet, but I don&#039;t eat anything that can&#039;t safely be eaten raw. I always counter with arguments about the toxicity of raw legumes, the anti-nutrients in whole grains and the calorie cost vs benefit to primitive people in making grains edible. The one thing I don&#039;t have a good grasp on is just how much the protease inhibitors in these foods limit the assimilation of amino acids. If an individual eats soy for protein, just how much of the soy&#039;s protein content is nullified by trypsin inhibitors, etc? I realize it&#039;s difficult to know precisely, given the cooking method and the form the food takes (TSP, soy milk, tofu) but is there any type of formula or table?  Can you point me to any studies with actual numbers to help bolster my argument?

Thanks so much!
Paleo Huntress

&lt;em&gt;I wish I could, but I don&#039;t have any such studies at hand.  I suspect, though, that the effect is significant.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>Dr. Eades,</p>
<p>I maintain a paleo-health community online (but do NOT subscribe to the low-fat PC&#8217;d book version of the diet) and regularly share entries from this blog with its members- THIS one was especially significant to us. One of the arguments I get quite a bit from newbies is about all of the &#8220;protein&#8221; in legumes, and whole grains, blah blah. I don&#8217;t eat a raw diet, but I don&#8217;t eat anything that can&#8217;t safely be eaten raw. I always counter with arguments about the toxicity of raw legumes, the anti-nutrients in whole grains and the calorie cost vs benefit to primitive people in making grains edible. The one thing I don&#8217;t have a good grasp on is just how much the protease inhibitors in these foods limit the assimilation of amino acids. If an individual eats soy for protein, just how much of the soy&#8217;s protein content is nullified by trypsin inhibitors, etc? I realize it&#8217;s difficult to know precisely, given the cooking method and the form the food takes (TSP, soy milk, tofu) but is there any type of formula or table?  Can you point me to any studies with actual numbers to help bolster my argument?</p>
<p>Thanks so much!<br />
Paleo Huntress</p>
<p><em>I wish I could, but I don&#8217;t have any such studies at hand.  I suspect, though, that the effect is significant.</em></p>
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		<title>By: Jean</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-211713</link>
		<dc:creator>Jean</dc:creator>
		<pubDate>Sat, 25 Apr 2009 18:10:55 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-211713</guid>
		<description>I have chronic neuropathy from a neck injury. I&#039;ve taken benfotiamine for several years now. I also take a narcotic, but at a dose that doesn&#039;t really treat the burning and tingling completely. The benfotiamine just about takes care of it all. I went off of it for a few months and realized that the stuff really works. I take 600mg a day in divided doses.</description>
		<content:encoded><![CDATA[<p>I have chronic neuropathy from a neck injury. I&#8217;ve taken benfotiamine for several years now. I also take a narcotic, but at a dose that doesn&#8217;t really treat the burning and tingling completely. The benfotiamine just about takes care of it all. I went off of it for a few months and realized that the stuff really works. I take 600mg a day in divided doses.</p>
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		<title>By: Lyn P</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-211343</link>
		<dc:creator>Lyn P</dc:creator>
		<pubDate>Fri, 24 Apr 2009 01:57:46 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-211343</guid>
		<description>Hi Doc, an update re my response to adding benfotiamine and R-lipoic acid.  Started benf on 4/9, 150 mg/day, with intial drop in that night&#039;s bedtime BG &amp; following morning BG, then 150 mg twice/day, with a BG rise back to about 5 pts less -- but mood &amp; stress resiliance much improved.  Started R-ALA on 4/15, 50 mg for 2 days, then 100 mg twice/day.  Morning BGs 10 pts lower (now mid 120s) and still dropping.  BGs drop throughout day (still on 750 mg metformin twice day) to 100-115 by late afternoon.  Bedtime BG been 105 or less for several days now.

On mom&#039;s b-day yesterday, I ate food I&#039;ve not eaten since diabetes diagnosis last August..so shoot me, I fell off the super low carb eating plan *G* (got right back on the &#039;wagon&#039; again).  2 hr PP BG=199 (I really thought it&#039;d be higher), 104 mins later after 40 mins on bike BG=91...WOW!!!  Gotta assume I can still produce lots of insulin, just not as quickly as I used to when I had hypoglycemia.  This give me hope that when I finally lose the excess wt (seems like hundreds yet to lose) I&#039;ll have normal BG WITHOUT drugs as long as I eat LC &amp; continue to exercise...and the nasal CPAP can be retired. Though my wt hasn&#039;t budged in wks (coinciding with max tree pollens &amp; layoff actually, so no surprise there), my water intake has also been down.  I know the exercise &amp; increased water &amp; supplements along with LC food will see the wt start dropping. 

Thanks to all of you who suggested I try R-lipoic acid for the liver cell insulin resistance, it&#039;s working!

Special thanks to you Doc for posting the link to Brownlee&#039;s paper -- without I&#039;d never have learned about benfotiamine, the secret that no one tells diabetics about, the ones who need it most.</description>
		<content:encoded><![CDATA[<p>Hi Doc, an update re my response to adding benfotiamine and R-lipoic acid.  Started benf on 4/9, 150 mg/day, with intial drop in that night&#8217;s bedtime BG &amp; following morning BG, then 150 mg twice/day, with a BG rise back to about 5 pts less &#8212; but mood &amp; stress resiliance much improved.  Started R-ALA on 4/15, 50 mg for 2 days, then 100 mg twice/day.  Morning BGs 10 pts lower (now mid 120s) and still dropping.  BGs drop throughout day (still on 750 mg metformin twice day) to 100-115 by late afternoon.  Bedtime BG been 105 or less for several days now.</p>
<p>On mom&#8217;s b-day yesterday, I ate food I&#8217;ve not eaten since diabetes diagnosis last August..so shoot me, I fell off the super low carb eating plan *G* (got right back on the &#8216;wagon&#8217; again).  2 hr PP BG=199 (I really thought it&#8217;d be higher), 104 mins later after 40 mins on bike BG=91&#8230;WOW!!!  Gotta assume I can still produce lots of insulin, just not as quickly as I used to when I had hypoglycemia.  This give me hope that when I finally lose the excess wt (seems like hundreds yet to lose) I&#8217;ll have normal BG WITHOUT drugs as long as I eat LC &amp; continue to exercise&#8230;and the nasal CPAP can be retired. Though my wt hasn&#8217;t budged in wks (coinciding with max tree pollens &amp; layoff actually, so no surprise there), my water intake has also been down.  I know the exercise &amp; increased water &amp; supplements along with LC food will see the wt start dropping. </p>
<p>Thanks to all of you who suggested I try R-lipoic acid for the liver cell insulin resistance, it&#8217;s working!</p>
<p>Special thanks to you Doc for posting the link to Brownlee&#8217;s paper &#8212; without I&#8217;d never have learned about benfotiamine, the secret that no one tells diabetics about, the ones who need it most.</p>
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		<title>By: dianne Gariepy</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-211033</link>
		<dc:creator>dianne Gariepy</dc:creator>
		<pubDate>Wed, 22 Apr 2009 18:30:08 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-211033</guid>
		<description>Nick,  I did go to that link about the supplements.  

Well, you know I take a chromium supplement, and it has magnesium in it and B1 in it and a whole lot of other things and it is a vit supplement system worked out for diabetics.  When I don&#039;t take it for a week or two, my BS goes up,  insulen requirement goes up.  when I do take it, the BS goes down, and insulen requirments go down.  So this pretty much flies in the face of what that link is telling us. 

The best research I have is what my body tells me is the results.  As Dr. Mike has taught us studies are not always what they seem and can be slanted to what the researcher wanted to have turn out.

I know what works for my body.  PP diet, low to no carbs does, and the vits work for me, although I have had plenty who tell me wrong diet, include grains etc, and give me noise because of the vits,  they work for me, that is all that I need.</description>
		<content:encoded><![CDATA[<p>Nick,  I did go to that link about the supplements.  </p>
<p>Well, you know I take a chromium supplement, and it has magnesium in it and B1 in it and a whole lot of other things and it is a vit supplement system worked out for diabetics.  When I don&#8217;t take it for a week or two, my BS goes up,  insulen requirement goes up.  when I do take it, the BS goes down, and insulen requirments go down.  So this pretty much flies in the face of what that link is telling us. </p>
<p>The best research I have is what my body tells me is the results.  As Dr. Mike has taught us studies are not always what they seem and can be slanted to what the researcher wanted to have turn out.</p>
<p>I know what works for my body.  PP diet, low to no carbs does, and the vits work for me, although I have had plenty who tell me wrong diet, include grains etc, and give me noise because of the vits,  they work for me, that is all that I need.</p>
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		<title>By: Soulnik</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-211014</link>
		<dc:creator>Soulnik</dc:creator>
		<pubDate>Wed, 22 Apr 2009 16:52:50 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-211014</guid>
		<description>Does anyone reading this blog take the fat-soluble version 
of thiamin called sulbutiamine? 

I take benfotiamine and vitamin B1 but have yet to try sulbutiamine.

Sulbutiamine study:

&quot;Effects of Sulbutiamine on diabetic polyneuropathy: An open randomised 
controlled study in type 2 diabetics&quot;

http://www.bioline.org.br/request?mj02005</description>
		<content:encoded><![CDATA[<p>Does anyone reading this blog take the fat-soluble version<br />
of thiamin called sulbutiamine? </p>
<p>I take benfotiamine and vitamin B1 but have yet to try sulbutiamine.</p>
<p>Sulbutiamine study:</p>
<p>&#8220;Effects of Sulbutiamine on diabetic polyneuropathy: An open randomised<br />
controlled study in type 2 diabetics&#8221;</p>
<p><a href="http://www.bioline.org.br/request?mj02005" rel="nofollow">http://www.bioline.org.br/request?mj02005</a></p>
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		<title>By: Nick</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-210893</link>
		<dc:creator>Nick</dc:creator>
		<pubDate>Wed, 22 Apr 2009 03:42:43 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-210893</guid>
		<description>This is a great post, thank you Dr. Eades.  It is also a good reminder for those who have issues with blood sugar control to keep tabs on Jenny Ruhl&#039;s website and blog also, as she has an excellent page on diabetes and supplements, including a reference to this study.

http://www.phlaunt.com/diabetes/20144672.php</description>
		<content:encoded><![CDATA[<p>This is a great post, thank you Dr. Eades.  It is also a good reminder for those who have issues with blood sugar control to keep tabs on Jenny Ruhl&#8217;s website and blog also, as she has an excellent page on diabetes and supplements, including a reference to this study.</p>
<p><a href="http://www.phlaunt.com/diabetes/20144672.php" rel="nofollow">http://www.phlaunt.com/diabetes/20144672.php</a></p>
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		<title>By: Anna</title>
		<link>http://www.proteinpower.com/drmike/supplements/thiamin-and-diabetic-nephropathy/#comment-210797</link>
		<dc:creator>Anna</dc:creator>
		<pubDate>Tue, 21 Apr 2009 17:09:28 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2869#comment-210797</guid>
		<description>Gisela,

Even with the lower carb intake, consider avoiding wheat &amp; gluten-derived ingredients. Some of those symptoms you describe (peripheral tingling esp) are also common with gluten sensitivity/celiac.  Some low carb foods (LC breads variations) are very high in added gluten (used to boost protein and reduce starch), so one can be eating LC, but actually ingesting a LOT of gluten.  Soy is also often increased in these LC foods, too.  Better to stick to foods naturally low in carbs instead of LC franken foods that might be increasing your exposure to problematic ingredients like gluten and processed soy.</description>
		<content:encoded><![CDATA[<p>Gisela,</p>
<p>Even with the lower carb intake, consider avoiding wheat &amp; gluten-derived ingredients. Some of those symptoms you describe (peripheral tingling esp) are also common with gluten sensitivity/celiac.  Some low carb foods (LC breads variations) are very high in added gluten (used to boost protein and reduce starch), so one can be eating LC, but actually ingesting a LOT of gluten.  Soy is also often increased in these LC foods, too.  Better to stick to foods naturally low in carbs instead of LC franken foods that might be increasing your exposure to problematic ingredients like gluten and processed soy.</p>
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