Comments on: Leptin, low-carb and hunger

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The Infertility Cure Randine Lewis Pdf — Wed, 29 Feb 2012 14:00:47 +0000

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By: StandardModel

StandardModel — Sat, 25 Feb 2012 13:14:34 +0000

I may be one of the few people who would benefit from Leptin therapy. I am obese but have a circulating Leptin level close to zero. As a result, I have type 2 diabetes and metabolic syndrome.

It’s not the typical situation with obese people where they have plenty of circulating Leptin but triglycerides prevent absorption of it. For some reason, I don’t produce it at all. Wouldn’t you think Metreleptin would help?

By: Priscilla

Priscilla — Wed, 21 Dec 2011 03:24:42 +0000

Hi, thanks for the very informative article. I have a question. Do you know what a healthy child’s leptin level should be? (more specifically a 4 year old) I had my daughter’s tested and it was a 9.9. I read online that it should be around 2.2. Any answers would be greatly appreciated. Thanks again

By: 200 pound 3rd grader is taken from his home | Mark's Daily Apple Health and Fitness Forum page

Tue, 29 Nov 2011 17:37:02 +0000

[...] That poor kid is probably leptin deficient. The Blog of Michael R. Eades, M.D. � Leptin, low-carb and hunger Female, 5'3", 160lbs. Would like to be 120lbs. My infrequently kept journal Reply [...]

By: Obesity starts in the brain / Getting Stronger

Obesity starts in the brain / Getting Stronger — Sat, 26 Nov 2011 08:14:23 +0000

[...] connection between triglycerides, the blood brain barrier and appetite in his 2007 blog post “Leptin, low-carb and hunger“. But I suspect that it is specifically the effect of fructose reduction — and not the [...]

By: John Polagruto, PhD

John Polagruto, PhD — Thu, 27 Oct 2011 19:43:47 +0000

Dr. Eades, as a college nutrition instructor, I do appreciate the article. I myself am an unabashed fan of lower carb diets, but even after reading (and frequently touting) Gary Taubes’ two books on weight, I am not convinced that lower carb diets are for every body. Certainly, many people do successfully maintain their weight on a 50% kcals from carbohydrates diet.

The first question I would ask is – can we identify those who successfully respond to a low carb diet? Would you guestimate that fasting triglycerides (without a genetic propensity for elevated triglycerides) might be that marker?

Secondly, having seen my TG’s fall to ~ 50 mg/dL after taking fish oil for 6 mos. (to raise my HDL from 39 to 50 mg/dL), would omega-3 fats provide a means by which the obese could more greatly respond to their circulating levels of leptin? (via omega-3 reductions in TGs).

Thanks,

John P

PS Off to go teach nutrition to a class full of Gatorade sipping undergrads!

By: Brigitta

Brigitta — Fri, 26 Aug 2011 18:15:10 +0000

Hi Dr. Eades,

This blog post is going in the “best of” section in my bookmarks for your blog.

If people really want to lose weight, the key is to make it as easy as possible for leptin to cross the BBB. And to do that, decrease triglycerides. To reduce triglycerides, cut out all unnecessary carbs like foods high in starch as well as anything with sugar.

The above paragraph I wrote (I feel) summarizes what you’re trying to communicate and is something that doctors should tell their patients (especially the obese ones) WORD FOR WORD.

About my weightloss: I realized in January 2011 that I had put on over 30 pounds since college, so I went back on a low-carb diet. I cut my carb intake at first to 20-30 grams per day. Now my maximum (in italics) intake is 40 grams a day. I have not been doing any kind of exercise since then, mainly because I’m lazy but I do think it has its benefits. Despite the fact that I didn’t exercise, I have lost 23 pounds. I’m 5’9 and my goal weight is at least 145. I’ve got 8 more pounds to lose and they’re steadily coming off with barely any effort on my part

I haven’t been following any specific low-carb plan, but I think your book PPLP was extremely helpful. Especially the chapter on insulin. The first LC book I ever read was Atkins New Diet Revolution in high school and he had a chapter on insulin as well, but your version was more in depth. PPLP is on my book shelf and I’ll probably give it a second read. It is that good.

By: tricia bowers

tricia bowers — Wed, 17 Aug 2011 17:16:30 +0000

My issues seem to be a little different than others. I have no appetite, food nauseates me and has for the last 9 months. I basically force myself to eat dinner – meat & veggies. Yet, have gained 30 lbs during this time period. I have recently purchased some desccicated liver tabs and am using them in place of meals. I am being treated w/ armour thyroid, 4 grains & cortef 30 mg, divided into 4 doses daily. My weight has not budged. I now weigh 175, my most comfortable weight is 145. I did weigh 260 in 1995 and lost it over a year with low carb and have maintained that regimen for all these years, so I do understand how it works. I did have the reverse t3 test done and it is quite high. Any ideas, suggestions out there would sure be appreciated.

By: Low Carb Age » Leptin Resistance

Low Carb Age » Leptin Resistance — Thu, 07 Apr 2011 16:37:46 +0000

[...] the curious case of leptin resistance, where this essential hormone is blocked by the BBB? As Dr. Mike Eades explains: Research done a couple of years ago in St. Louis and in Japan pinpointed the problem. [...]

By: Low Carb Diets & Hormones

Low Carb Diets & Hormones — Sun, 15 Aug 2010 22:46:47 +0000

[...] intake. For those who consume lower carb they actually 'need' less leptin to get the same effect Leptin, low-carb and hunger | The Blog of Michael R. Eades, M.D. Quote When you eat the foods your body is made for (Paleo foods) in a framework that [...]