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	<title>Comments on: A quest fulfilled</title>
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	<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/</link>
	<description>A critical look at nutritional science and anything else that strikes my fancy.</description>
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		<title>By: jeff</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-2/#comment-215121</link>
		<dc:creator>jeff</dc:creator>
		<pubDate>Tue, 19 May 2009 14:40:08 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-215121</guid>
		<description>Just found this on Drudge Report.  After reading just a little bit of Lucy, I think this must be wrong:

MONKEY SKULL FOUND: THE LINK IN HUMAN EVOLUTION?

&lt;em&gt;This fossil predates Lucy by about 40 million years.  It is supposedly the ancestor of all primates, but I&#039;ll be curious to see what kind of controversy it stirs up once all the paleontologists get a chance to evaluate it.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>Just found this on Drudge Report.  After reading just a little bit of Lucy, I think this must be wrong:</p>
<p>MONKEY SKULL FOUND: THE LINK IN HUMAN EVOLUTION?</p>
<p><em>This fossil predates Lucy by about 40 million years.  It is supposedly the ancestor of all primates, but I&#8217;ll be curious to see what kind of controversy it stirs up once all the paleontologists get a chance to evaluate it.</em></p>
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		<title>By: Lyn P</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-2/#comment-207706</link>
		<dc:creator>Lyn P</dc:creator>
		<pubDate>Fri, 27 Mar 2009 02:53:52 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-207706</guid>
		<description>Hey Doc, thanks for the heads up re estrogen release from fat cells.  Could this be why my TST levels are flucuating between 2 and 4 like a yoyo?  Lost 50 #s so far, BGs finally averaging in the 120s. Still on Mazxide, down to 750 ER Metformin, dropped Januvia &amp; Cozaar in Jan...delighted with my progress &amp; continuing wt loss, still have lots to lose.  &#039;nother question:  fell last month (then cellulitis, IV antibiotics, and got laidoff)...stress drove average BGs to 140, then my systolic BP went up.  I had to add 1/4 dose Cozaar to get it back down.  If I understand the Brownlee article (you posted a link) on the pathobiology of diabetic complications, did my BP go up as my endothelial cells were irritated, um, damaged from first the infection, then IV treatment, and finally the increased BGs?  If that is true, then I can drop the Cozaar unless my average BGs start going higher than the high 130s (I really dislike the breathlessness that I get with continued dosing of Cozaar).  Or, did he mean long-term effects and not relatively short-term effects as I appear to have experienced -- or am I making unreasonable assumptions?

from his article: 
&quot;thiamine derivative called benfotiamine&quot; is this safe to take?  I read that some report reduced systolic taking 150 mgs twice/day
&quot;PARP inhibitor&quot; is there one that is safe to take?
&quot;SOD/catalase mimetic&quot; is there one that is safe to take?

Brownlee presents powerful albeit non-human evidence for his theory of a unified cause of the pathobiology.

&lt;em&gt;I&#039;m sorry, but medico-legal issues prevent me from being able to answer specific medical questions.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>Hey Doc, thanks for the heads up re estrogen release from fat cells.  Could this be why my TST levels are flucuating between 2 and 4 like a yoyo?  Lost 50 #s so far, BGs finally averaging in the 120s. Still on Mazxide, down to 750 ER Metformin, dropped Januvia &amp; Cozaar in Jan&#8230;delighted with my progress &amp; continuing wt loss, still have lots to lose.  &#8216;nother question:  fell last month (then cellulitis, IV antibiotics, and got laidoff)&#8230;stress drove average BGs to 140, then my systolic BP went up.  I had to add 1/4 dose Cozaar to get it back down.  If I understand the Brownlee article (you posted a link) on the pathobiology of diabetic complications, did my BP go up as my endothelial cells were irritated, um, damaged from first the infection, then IV treatment, and finally the increased BGs?  If that is true, then I can drop the Cozaar unless my average BGs start going higher than the high 130s (I really dislike the breathlessness that I get with continued dosing of Cozaar).  Or, did he mean long-term effects and not relatively short-term effects as I appear to have experienced &#8212; or am I making unreasonable assumptions?</p>
<p>from his article:<br />
&#8220;thiamine derivative called benfotiamine&#8221; is this safe to take?  I read that some report reduced systolic taking 150 mgs twice/day<br />
&#8220;PARP inhibitor&#8221; is there one that is safe to take?<br />
&#8220;SOD/catalase mimetic&#8221; is there one that is safe to take?</p>
<p>Brownlee presents powerful albeit non-human evidence for his theory of a unified cause of the pathobiology.</p>
<p><em>I&#8217;m sorry, but medico-legal issues prevent me from being able to answer specific medical questions.</em></p>
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		<title>By: Debbie</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-2/#comment-207576</link>
		<dc:creator>Debbie</dc:creator>
		<pubDate>Wed, 25 Mar 2009 17:01:17 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-207576</guid>
		<description>What a cool post this was. I&#039;ve had a passing interest in paleoanthropology since reading the gripping children&#039;s book, &#039;The First Men in the World&#039; by Anne Terry White some 40+ years ago (pre -Lucy). I loved that book so much I read it multiple times in my childhood, but had not read anything on the subject in years. After reading this blog post I took &quot;Lucy&quot; from the library. What a fascinating read. Interesting that A. robustus, with the large crushing molars designed to break down plant materials came to a dead-end, but the smaller-molared, more omniverously-oriented teeth found in Lucy and her kind were the sort that continued on into genus Homo. 

But thinking of those teeth help keep my focused during discouraging weeks like this one where I&#039;ve currently gained five pounds, despite staying faithfully low carb, sugar-free, grain-free, and keeping my ECC in the 20-40 range. (and no it&#039;s not any sort of pre-menstrual fluid gain since I&#039;m some years past that).  Sad to think that calories must still count. Even on low carb I can not seem to be able to eat enough to be satisfied and hope to lose weight.

&lt;em&gt;I&#039;m glad you enjoyed Lucy.  It&#039;s the best, by far, of all the books that have come along since.  BTW, I met Johanson this past weekend at a conference.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>What a cool post this was. I&#8217;ve had a passing interest in paleoanthropology since reading the gripping children&#8217;s book, &#8216;The First Men in the World&#8217; by Anne Terry White some 40+ years ago (pre -Lucy). I loved that book so much I read it multiple times in my childhood, but had not read anything on the subject in years. After reading this blog post I took &#8220;Lucy&#8221; from the library. What a fascinating read. Interesting that A. robustus, with the large crushing molars designed to break down plant materials came to a dead-end, but the smaller-molared, more omniverously-oriented teeth found in Lucy and her kind were the sort that continued on into genus Homo. </p>
<p>But thinking of those teeth help keep my focused during discouraging weeks like this one where I&#8217;ve currently gained five pounds, despite staying faithfully low carb, sugar-free, grain-free, and keeping my ECC in the 20-40 range. (and no it&#8217;s not any sort of pre-menstrual fluid gain since I&#8217;m some years past that).  Sad to think that calories must still count. Even on low carb I can not seem to be able to eat enough to be satisfied and hope to lose weight.</p>
<p><em>I&#8217;m glad you enjoyed Lucy.  It&#8217;s the best, by far, of all the books that have come along since.  BTW, I met Johanson this past weekend at a conference.</em></p>
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		<title>By: Andrea L.</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-2/#comment-206480</link>
		<dc:creator>Andrea L.</dc:creator>
		<pubDate>Sat, 14 Mar 2009 22:15:21 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-206480</guid>
		<description>Dan wrote: So here’s the best nutritional advice our national news broadcaster (CBC) can come up with - unbelievable!

http://www.cbc.ca/health/story/2009/03/11/f-nutritionmyths.html

Andrea admonished: Be fair, now, at least the brown vs. white eggs issue was resolved properly, and the writer admits that eating eggs does not raise cholesterol. One and a half right out of ten is...okay it&#039;s frightening.</description>
		<content:encoded><![CDATA[<p>Dan wrote: So here’s the best nutritional advice our national news broadcaster (CBC) can come up with &#8211; unbelievable!</p>
<p><a href="http://www.cbc.ca/health/story/2009/03/11/f-nutritionmyths.html" rel="nofollow">http://www.cbc.ca/health/story/2009/03/11/f-nutritionmyths.html</a></p>
<p>Andrea admonished: Be fair, now, at least the brown vs. white eggs issue was resolved properly, and the writer admits that eating eggs does not raise cholesterol. One and a half right out of ten is&#8230;okay it&#8217;s frightening.</p>
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		<title>By: Jeremy</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-2/#comment-206383</link>
		<dc:creator>Jeremy</dc:creator>
		<pubDate>Fri, 13 Mar 2009 19:47:22 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-206383</guid>
		<description>Wow. Sorry for the poor grammar. It was late.
&lt;em&gt;No problem.  I do it, too.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>Wow. Sorry for the poor grammar. It was late.<br />
<em>No problem.  I do it, too.</em></p>
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		<title>By: Dan</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-1/#comment-206312</link>
		<dc:creator>Dan</dc:creator>
		<pubDate>Thu, 12 Mar 2009 15:13:16 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-206312</guid>
		<description>So here&#039;s the best nutritional advice our national news broadcaster (CBC) can come up with - unbelievable! 

http://www.cbc.ca/health/story/2009/03/11/f-nutritionmyths.html

It&#039;s going to be a long slow road to getting the truth out to people, please don&#039;t lose heart, Drs. Eades!
&lt;em&gt;You don&#039;t have to read much of this drivel before you realize you&#039;re in the presence of a real dolt. How do these people get published?&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>So here&#8217;s the best nutritional advice our national news broadcaster (CBC) can come up with &#8211; unbelievable! </p>
<p><a href="http://www.cbc.ca/health/story/2009/03/11/f-nutritionmyths.html" rel="nofollow">http://www.cbc.ca/health/story/2009/03/11/f-nutritionmyths.html</a></p>
<p>It&#8217;s going to be a long slow road to getting the truth out to people, please don&#8217;t lose heart, Drs. Eades!<br />
<em>You don&#8217;t have to read much of this drivel before you realize you&#8217;re in the presence of a real dolt. How do these people get published?</em></p>
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		<title>By: Jeremy</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-1/#comment-206295</link>
		<dc:creator>Jeremy</dc:creator>
		<pubDate>Thu, 12 Mar 2009 03:49:32 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-206295</guid>
		<description>Hey Doc,

My psychology professor and I got into an argument about how the brain processes energy. I said that while the brain will use glucose primarily it can use keytones and they are actually preferred. He was trying to say that it is a last resort in starvation, etc. 

Is there any studies that are available to show him? 

Thanks

&lt;em&gt;Evidence seems to indicate that ketones may be the preferred fuel for the brain.  It&#039;s a tricky explanation as to why and better reserve for an entire post.  Off the top of my head, I don&#039;t know any specific studies to show your professor, but if he&#039;s smart and has a logical mind, he ought to be able to figure it out.  I just did, tooling down the highway at 79 miles an hour.&lt;/em&gt; </description>
		<content:encoded><![CDATA[<p>Hey Doc,</p>
<p>My psychology professor and I got into an argument about how the brain processes energy. I said that while the brain will use glucose primarily it can use keytones and they are actually preferred. He was trying to say that it is a last resort in starvation, etc. </p>
<p>Is there any studies that are available to show him? </p>
<p>Thanks</p>
<p><em>Evidence seems to indicate that ketones may be the preferred fuel for the brain.  It&#8217;s a tricky explanation as to why and better reserve for an entire post.  Off the top of my head, I don&#8217;t know any specific studies to show your professor, but if he&#8217;s smart and has a logical mind, he ought to be able to figure it out.  I just did, tooling down the highway at 79 miles an hour.</em></p>
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		<title>By: Kennedy</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-1/#comment-206259</link>
		<dc:creator>Kennedy</dc:creator>
		<pubDate>Wed, 11 Mar 2009 13:16:28 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-206259</guid>
		<description>You might like the book Big Brain by Richard Granger and Gary Lynch, of which a good chunk is about the Boskops and their huge skulls in the 1900 cc range, dating from around 10,000 years ago in South Africa.

Have been reading your blog and books for just over a year now and have gained so much.

Many thanks

&lt;em&gt;Thanks for the book tip.  I haven&#039;t read that one.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>You might like the book Big Brain by Richard Granger and Gary Lynch, of which a good chunk is about the Boskops and their huge skulls in the 1900 cc range, dating from around 10,000 years ago in South Africa.</p>
<p>Have been reading your blog and books for just over a year now and have gained so much.</p>
<p>Many thanks</p>
<p><em>Thanks for the book tip.  I haven&#8217;t read that one.</em></p>
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		<title>By: NCbeth</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-1/#comment-206233</link>
		<dc:creator>NCbeth</dc:creator>
		<pubDate>Wed, 11 Mar 2009 00:52:02 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-206233</guid>
		<description>Typing in a rush...trying to get two kids to bed shortly...my apologiesI bumped into some info in the past few days...not sure if you have addressed it here previously, and I don&#039;t remember seeing it in your new book (although maybe I should reread).
Does fish oil negatively impact blood sugar?  The FDA (I know, useless ;) ) says something about reduced glycemic control in diabetics using EPA/DHA/Omega 3 supplements?

I haven&#039;t pulled up the original study but the blurb I read listed this reference:
 Stacpoole, P, Alig, A., Ammon, L, October), 1989, pages 946-956 (this was how it was listed...no journal name).

It also mentioned another study
The report is titled “Omega 3 Polyunsaturated Fatty Acids, Inflammation and Immunity,” by Philip C. Calder, Institute of Human Nutrition, University of Southampton, Bassett Crescent East, Southampton, UK.

Supposedly indicating that fish oil may suppress some immune function?

LIke I said, I haven&#039;t had time to go digging yet, but if you are familiar w/ these studies I was wondering if you might comment.  As a non-overweight woman with PCOS, I&#039;m trying to figure out whether fish oil might worsen insulin resistance? (I don&#039;t test + for IR based on a 2 hour GTT but I do better on metformin and eating lower carb, at least in terms of it making my cycles (somewhat) more regular.

&lt;em&gt;In my experience fish oil neither suppresses immunity nor destabilizes blood sugar levels.  If you are concerned yet want to increase intake of omega-3 fats, try krill oil.  You get less EPA/DHA but more bioavailability.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>Typing in a rush&#8230;trying to get two kids to bed shortly&#8230;my apologiesI bumped into some info in the past few days&#8230;not sure if you have addressed it here previously, and I don&#8217;t remember seeing it in your new book (although maybe I should reread).<br />
Does fish oil negatively impact blood sugar?  The FDA (I know, useless <img src='http://www.proteinpower.com/drmike/wp-includes/images/smilies/icon_wink.gif' alt=';)' class='wp-smiley' />  ) says something about reduced glycemic control in diabetics using EPA/DHA/Omega 3 supplements?</p>
<p>I haven&#8217;t pulled up the original study but the blurb I read listed this reference:<br />
 Stacpoole, P, Alig, A., Ammon, L, October), 1989, pages 946-956 (this was how it was listed&#8230;no journal name).</p>
<p>It also mentioned another study<br />
The report is titled “Omega 3 Polyunsaturated Fatty Acids, Inflammation and Immunity,” by Philip C. Calder, Institute of Human Nutrition, University of Southampton, Bassett Crescent East, Southampton, UK.</p>
<p>Supposedly indicating that fish oil may suppress some immune function?</p>
<p>LIke I said, I haven&#8217;t had time to go digging yet, but if you are familiar w/ these studies I was wondering if you might comment.  As a non-overweight woman with PCOS, I&#8217;m trying to figure out whether fish oil might worsen insulin resistance? (I don&#8217;t test + for IR based on a 2 hour GTT but I do better on metformin and eating lower carb, at least in terms of it making my cycles (somewhat) more regular.</p>
<p><em>In my experience fish oil neither suppresses immunity nor destabilizes blood sugar levels.  If you are concerned yet want to increase intake of omega-3 fats, try krill oil.  You get less EPA/DHA but more bioavailability.</em></p>
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		<title>By: lark</title>
		<link>http://www.proteinpower.com/drmike/low-carb-library/a-quest-fulfilled/comment-page-1/#comment-206230</link>
		<dc:creator>lark</dc:creator>
		<pubDate>Tue, 10 Mar 2009 23:21:10 +0000</pubDate>
		<guid isPermaLink="false">http://www.proteinpower.com/drmike/?p=2692#comment-206230</guid>
		<description>Thanks for posting about the Lucy exhibit! We were in Seattle on Saturday to visit my parents and invited them to go see it with us. I thought the exhibit was really disjointed (no pun intended) as far as the Ethiopia part (focused on religion and political history) having little connection with the Lucy exhibit and the film afterward.

As far as the Lucy exhibit itself, it was amazing. You&#039;ve pretty much said it all, though did you check out the mural depicting the evolution of H. Sapiens? The earliest scene depicting A. Kadabba reaching for a firefly immediately made me flash on the Michelangelo&#039;s &quot;Creation of Adam&quot; in the Sistine Chapel. Somehow I doubt the resemblence was accidental.

Off topic - I ordered two copies each of Fat Head and Lucy (the book) from Amazon via your site. I enjoyed the movie very much, and will give the other copy to my parents. I think it will reach my mother better than GCBC (I couldn&#039;t get her to read it, though my father devoured it in a couple days). I wish the movie were shorter though, because aside from the length it would be the perfect &quot;wellness&quot; lunch time activity at work. I&#039;m afraid if I have to split it up over two sessions it won&#039;t reach nearly as many people. If you know of a similar resource that&#039;s no more than an hour long (or could maybe talk Tom Naughton into editing it down a bit) please let me know.

&lt;em&gt;Thanks very much for the orders through the site.  Unfortunately, I don&#039;t know of a shorter film on the benefits of low-carb.  Maybe other readers will.  I did love the mural.  I can&#039;t believe I didn&#039;t include something about it in my post.&lt;/em&gt;</description>
		<content:encoded><![CDATA[<p>Thanks for posting about the Lucy exhibit! We were in Seattle on Saturday to visit my parents and invited them to go see it with us. I thought the exhibit was really disjointed (no pun intended) as far as the Ethiopia part (focused on religion and political history) having little connection with the Lucy exhibit and the film afterward.</p>
<p>As far as the Lucy exhibit itself, it was amazing. You&#8217;ve pretty much said it all, though did you check out the mural depicting the evolution of H. Sapiens? The earliest scene depicting A. Kadabba reaching for a firefly immediately made me flash on the Michelangelo&#8217;s &#8220;Creation of Adam&#8221; in the Sistine Chapel. Somehow I doubt the resemblence was accidental.</p>
<p>Off topic &#8211; I ordered two copies each of Fat Head and Lucy (the book) from Amazon via your site. I enjoyed the movie very much, and will give the other copy to my parents. I think it will reach my mother better than GCBC (I couldn&#8217;t get her to read it, though my father devoured it in a couple days). I wish the movie were shorter though, because aside from the length it would be the perfect &#8220;wellness&#8221; lunch time activity at work. I&#8217;m afraid if I have to split it up over two sessions it won&#8217;t reach nearly as many people. If you know of a similar resource that&#8217;s no more than an hour long (or could maybe talk Tom Naughton into editing it down a bit) please let me know.</p>
<p><em>Thanks very much for the orders through the site.  Unfortunately, I don&#8217;t know of a shorter film on the benefits of low-carb.  Maybe other readers will.  I did love the mural.  I can&#8217;t believe I didn&#8217;t include something about it in my post.</em></p>
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