Almost ten years ago when we were in practice in Boulder, Colorado we started looking for a good weightloss supplement to help our
patients on low-carb diets lose a little more quickly. We evaluated a lot of supplements on the market that were supposedly weight loss accelerators – chromium, hydroxycitric acid (HCA), ephedra, phenylpropanolamine, pyruvate and a few others – with out a lot of success. The ephedra and, to a lesser extent, phenylpropanolamine unquestionably helped people lose weight, but were fraught with side effects. Pyruvate showed promise, but was pretty expensive. Our partner found a couple of medical papers using a combination of supplements, some of which individually didn’t work all that well but in combination seemed to show promise. We cobbled together from healthfood-store supplements a sort of beta-prototype of this combination and used it on a number of our willing patients. The vast majority, all of whom were on low-carb diets, tolerated the supplement and felt it made them lose weight better.
Happy with these results MD, our partner and I decided to take the next step and get an actual product made. We did, and let patients try it. Again, the patients liked the supplement and though they lost weight better on it. Although we, too, thought the patients did better, we couldn’t really say because we hadn’t compared the supplement with a placebo in a controlled fashion. We decided to take that next step.
We contacted a clinical lab that does testing for a fee (a substantial fee, I might add) and talked to the director of the facility, who was pretty discouraging. He told us that he would be happy to take our money and test our supplement, but that we shouldn’t get our hopes up. He related that his company had tested scores of nutritional supplements and had never found one that really did much. And that he figured ours wouldn’t do well against placebo either.
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