Comments on: Statinators spill the beans http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/ A critical look at nutritional science and anything else that strikes my fancy. Thu, 09 Feb 2012 14:38:34 +0000 hourly 1 http://wordpress.org/?v=3.3.1 By: Question from a reader | The Low-Carb Curmudgeon http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-251401 Question from a reader | The Low-Carb Curmudgeon Fri, 05 Aug 2011 12:05:53 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-251401 [...] Statinators spill the beans [...] [...] Statinators spill the beans [...]

]]> By: George D. Henderson http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-247482 George D. Henderson Sun, 21 Nov 2010 23:54:57 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-247482 Niacinamide can cause depression by lowering adrenaline. But if you have anxiety, this is a good thing; and niacinamide also elevates low serotonin levels. So it is more likely to help an anxious, depressed person than it is to depress a normal person, which takes a higher dose. Here we have a non-addictive vitamin which can replace statins, prozac and valium. Generally vitamins and antioxidants are talked up enough online and I feel no need to add to that. But niacin and niacinamide, because of their misunderstood reputation for toxicity (which happens in very rare cases, usually for good reasons) is neglected. So I have no hesitation in broadcasting the fact that this stuff is a panacea, in the same class as vitamin D and ascorbic acid. It needs (debateably) a little more care in its use, but can produce at least as impressive results. Niacinamide can cause depression by lowering adrenaline. But if you have anxiety, this is a good thing; and niacinamide also elevates low serotonin levels. So it is more likely to help an anxious, depressed person than it is to depress a normal person, which takes a higher dose.
Here we have a non-addictive vitamin which can replace statins, prozac and valium. Generally vitamins and antioxidants are talked up enough online and I feel no need to add to that. But niacin and niacinamide, because of their misunderstood reputation for toxicity (which happens in very rare cases, usually for good reasons) is neglected.
So I have no hesitation in broadcasting the fact that this stuff is a panacea, in the same class as vitamin D and ascorbic acid. It needs (debateably) a little more care in its use, but can produce at least as impressive results.

]]> By: George D. Henderson http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-247481 George D. Henderson Sun, 21 Nov 2010 23:43:07 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-247481 I have given a great deal of study and thought to niacin as I am using it to treat liver disease - as an antifibrotic - and it appears to have worked. I use mainly niacinamide and no-flush niacin. These will lower LDL - it just takes longer; and raise HDL, perhaps more quickly. Niacin is converted to niacinamide, which requires glutamine (no problem on a high-protein diet), and any excess is converted to methyl-nicotinamide for excretion. this makes it a strong methyl-acceptor, which can cause the problems. For one thing, it lowers production of adrenaline, so can cause depression. But if you supplement B12 (preferably methylcobalamin) and folic acid you should never get these problems, at least I never did. High doses of niacinamide can elevate homocysteine, B12 and folate lowers homocysteine, so we're OK there. Niacin(amide) protects nitric oxide production by lowering asymetrical dimethyl-arginine (ADMA), which inhibits NO. Niacinamide inhibits the activation of hepatic stellate cells (HSCs), which cause liver fibrosis and cirrhosis, and induces apoptosis of activated HSCs. This makes it very protective of the liver in chronic conditions such as Hep C or alcoholism. It is also proven to be effective against rheumatoid arthritis. In general it lowers symptoms associated with many autoimmune diseases and allergies. And of course it is the supplement of choice in schizophrenia and bipolar disorders. If it was a drug, it would be as popular as aspirin. Or, statins... I have given a great deal of study and thought to niacin as I am using it to treat liver disease – as an antifibrotic – and it appears to have worked.
I use mainly niacinamide and no-flush niacin. These will lower LDL – it just takes longer; and raise HDL, perhaps more quickly.
Niacin is converted to niacinamide, which requires glutamine (no problem on a high-protein diet), and any excess is converted to methyl-nicotinamide for excretion.
this makes it a strong methyl-acceptor, which can cause the problems. For one thing, it lowers production of adrenaline, so can cause depression. But if you supplement B12 (preferably methylcobalamin) and folic acid you should never get these problems, at least I never did.
High doses of niacinamide can elevate homocysteine, B12 and folate lowers homocysteine, so we’re OK there.
Niacin(amide) protects nitric oxide production by lowering asymetrical dimethyl-arginine (ADMA), which inhibits NO.
Niacinamide inhibits the activation of hepatic stellate cells (HSCs), which cause liver fibrosis and cirrhosis, and induces apoptosis of activated HSCs. This makes it very protective of the liver in chronic conditions such as Hep C or alcoholism. It is also proven to be effective against rheumatoid arthritis. In general it lowers symptoms associated with many autoimmune diseases and allergies. And of course it is the supplement of choice in schizophrenia and bipolar disorders.
If it was a drug, it would be as popular as aspirin. Or, statins…

]]> By: Joan Mercantini http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-247217 Joan Mercantini Wed, 10 Nov 2010 01:55:10 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-247217 Thank you so much, Dr. Eades for sharing all the information in this and the other articles on Statins. After taking Lipitor for approx. 15 years my husband developed sever leg pains and his pharmacist told him to stop immediately which he did, and the pains went away. He has been off Lipitor for 6 months and on his last blood test his cholesterol was elevated and his doctor has now prescribed Crestor. I am positive after reading Protein Power if he limits his carbs his cholesterol will come down., It is sad indeed that there is so much controversy about this .Needless to say I am keeping up with all your tweets. Kindest regards Joan Mercantini Thank you so much, Dr. Eades for sharing all the information in this and the other articles on Statins.
After taking Lipitor for approx. 15 years my husband developed sever leg pains and his pharmacist told him to stop immediately which he did, and the pains went away.
He has been off Lipitor for 6 months and on his last blood test his cholesterol was elevated and his doctor has now prescribed Crestor.
I am positive after reading Protein Power if he limits his carbs his cholesterol will come down., It is sad indeed that there is so much controversy about this .Needless to say I am keeping up with all your tweets. Kindest regards
Joan Mercantini

]]> By: charlie brown great pumpkin http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-247013 charlie brown great pumpkin Sun, 31 Oct 2010 16:08:47 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-247013 A story ran on national television two nights ago on the early signs of CVD risk showing up in young school age children. The story showed footage of public health officials screening children by taking their weight, blood pressure and testing their cholesterol (on the spot with a test kit). Apparently it only takes about 5 minutes to get the results of a cholesterol test done in this manner. One in six children were found to have high cholesterol which an official from public health stated in combination with saturated fat was "plugging the arteries" of these children. By this point I was starting to wonder what the motive is behind this campaign. Was it sincere concern over the development of CVD risk by our public health officials? if so, then they are either spectacularly incompetent or trying to deceive us. Whatever the reason I think it probable that the outcome will be that when the children with high cholesterol take their test results accompanied by the dire warnings that their arteries are clogging (pure, unsubstantiated speculation) home that most parents will rush their child to an MD who will promptly prescribe a good (expensive) brand of statin that they will probably be on for the rest of their life. To me this campaign reeks of a covert marketing program by the makers of statins whose real concern is their financial health. A story ran on national television two nights ago on the early signs of CVD risk showing up in young school age children. The story showed footage of public health officials screening children by taking their weight, blood pressure and testing their cholesterol (on the spot with a test kit). Apparently it only takes about 5 minutes to get the results of a cholesterol test done in this manner. One in six children were found to have high cholesterol which an official from public health stated in combination with saturated fat was “plugging the arteries” of these children.

By this point I was starting to wonder what the motive is behind this campaign. Was it sincere concern over the development of CVD risk by our public health officials? if so, then they are either spectacularly incompetent or trying to deceive us. Whatever the reason I think it probable that the outcome will be that when the children with high cholesterol take their test results accompanied by the dire warnings that their arteries are clogging (pure, unsubstantiated speculation) home that most parents will rush their child to an MD who will promptly prescribe a good (expensive) brand of statin that they will probably be on for the rest of their life.

To me this campaign reeks of a covert marketing program by the makers of statins whose real concern is their financial health.

]]> By: The V diet - Page 3 - Myprotein Forum http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-244504 The V diet - Page 3 - Myprotein Forum Wed, 12 May 2010 10:38:53 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-244504 [...] yet, but watch out for skin flushing with B3. It's harmless, but can be disconcerting at first. Statinators spill the beans | The Blog of Michael R. Eades, M.D. Also, don't know if you know this, but RYR is actually a naturally-occurring statin. Just [...] [...] yet, but watch out for skin flushing with B3. It's harmless, but can be disconcerting at first. Statinators spill the beans | The Blog of Michael R. Eades, M.D. Also, don't know if you know this, but RYR is actually a naturally-occurring statin. Just [...]

]]> By: Great links for the weekend! http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-244404 Great links for the weekend! Fri, 30 Apr 2010 20:05:28 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-244404 [...] discussion.  I’ve previously written about statins and I’ve now found this analysis by Michael Eades of a recent statins study.  What do you [...] [...] discussion.  I’ve previously written about statins and I’ve now found this analysis by Michael Eades of a recent statins study.  What do you [...]

]]> By: Colesterol HDL LDL VLDL trigliceride | Kaciula.ro http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-243120 Colesterol HDL LDL VLDL trigliceride | Kaciula.ro Thu, 25 Feb 2010 09:27:40 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-243120 [...] productia de hormoni, reglarea glicemiei. Doctor Eades are pornita o adevarata cruciada(cum ar fi aici sau aici) impotriva statins-urilor (Zetia, Lipitor etc.) insa nu multi doctori stau cu urechile [...] [...] productia de hormoni, reglarea glicemiei. Doctor Eades are pornita o adevarata cruciada(cum ar fi aici sau aici) impotriva statins-urilor (Zetia, Lipitor etc.) insa nu multi doctori stau cu urechile [...]

]]> By: 12/02/09 – AMRAP! http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-241877 12/02/09 – AMRAP! Wed, 02 Dec 2009 06:19:40 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-241877 [...] Another argument against Statins Going over the clean [...] [...] Another argument against Statins Going over the clean [...]

]]> By: Dr. Sekula on weight loss, fitness and nutrition » Blog Archive » statins and niacin … a concerted effort? http://www.proteinpower.com/drmike/cardiovascular-disease/statinators-spill-the-beans/#comment-241847 Dr. Sekula on weight loss, fitness and nutrition » Blog Archive » statins and niacin … a concerted effort? Mon, 30 Nov 2009 15:52:51 +0000 http://www.proteinpower.com/drmike/?p=3760#comment-241847 [...] In case you haven’t heard, statins and big pharma took it on the chin in a new study from the Journal of the American College of Cardiology. The results showed niacin was significantly more effective at reducing carotid artery plaque than statins alone. In fact, results showed plaque continuing to grow in the statins only group while regressing in the niacin group. I’m not going to detail the study and author’s conclusions, Dr. Eades has done a wonderful job of that. [...] [...] In case you haven’t heard, statins and big pharma took it on the chin in a new study from the Journal of the American College of Cardiology. The results showed niacin was significantly more effective at reducing carotid artery plaque than statins alone. In fact, results showed plaque continuing to grow in the statins only group while regressing in the niacin group. I’m not going to detail the study and author’s conclusions, Dr. Eades has done a wonderful job of that. [...]

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